Perfused Three-dimensional Organotypic Culture of Human Cancer Cells for Therapeutic Evaluation
نویسندگان
چکیده
منابع مشابه
Three-dimensional Organotypic Culture Models of Human Hepatocellular Carcinoma
Three-dimensional cell culture methods are viable in vitro approaches that facilitate the examination of biological features cancer cells present in vivo. In this study, we demonstrate that hepatocellular carcinoma (HCC) cells in porous alginate scaffolds can generate organoid-like spheroids that mimic numerous features of glandular epithelium in vivo, such as acinar morphogenesis and apical ex...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-09686-0